Scientist - Analytical Development Early Stage

Company: Takeda
Location: Cambridge
Posted on: April 5, 2026

Job Description:

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Scientist Analytical Development – Early Stage As a Scientist working in the Analytical Development Early Development team, you will be empowered tolead technical activities and represent Analytical Development Early Development within departmental and cross-functional team. POSITION OBJECTIVES: Support the transition of novel compounds (synthetic molecules, Oligonucleotide, Protacs) from Discovery into Development and development activities to support FIH clinical studies. The role will also involve continued research efforts throughout the developmental lifecycle of compounds across a wide range of activities. Interaction with Discovery Teams, Drug Safety , DMPK and close collaboration with Process Chemistry, Formulation development and Late Phase Analytical Development to achieve project goals. A strong focus will be on salt/polymorph screening, solid state analytics and analytical method development for API and Drug Product POSITION ACCOUNTABILITIES: Independently design, plan and execute studies on new development candidates to elucidate fundamental physicochemical properties and behaviors that enable lead candidate selection and downstream CMC development. Contributes to and drives solid state screening activities Lead physicochemical profiling efforts and analytical method development Contributes to a cross-functional Pharmaceutical Sciences team responsible for overseeing API salt and polymorph selection and subsequent development activities Develops analytical methods for release of GMP API and Drug Product. Responsible for significant technical leadership within a project and assist in project strategy development across projects within the department or cross functionally Interfaces with individual Pharmaceutical Science colleagues and cross functional project teams to ensure that development activities are consistent with physicochemical properties of API May serve as a technical expert/SME for mentoring of junior team members Responsible for integrating scientific/technical efforts around cross functional issues Plans and implements resolutions to technical problems/issues Supports local initiatives which may include technical or process related work streams Authoring of technical reports and contributes to regulatory filings EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS: Education and Experience: Required: Bachelors degree in Pharmaceutics, analytical chemistry, organic chemistry, or related pharmaceutical science with 8 years of relevant industry experience Masters degree in Pharmaceutics, physical organic chemistry, analytical chemistry, or related pharmaceutical science with 6 years of relevant industry experience PhD in relevant discipline with 0 years of relevant industry experience Knowledge and Skills: Strong understanding of polymorphism and solid state screening techniques Strong understanding of solid state analytical techniques (XRPD/DSC/TGA/DVS) Strong understanding of analytical method development (HPLC/GC/KF/Dissolution) and cGMP Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and identify/implement possible solutions Teamwork Ability to work well in highly cross functional team environment Communication Skills -Able to expresses one’s self clearly and concisely within teams; documents issues and/or concerns concisely with colleagues; timely and effective communication of issues to supervisor; technical writing skills to support authorship of internal technical documents Organization – Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information Resource Management -Ability to manage one’s time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors) Technical - strong knowledge analytical theory along with hands on experience in multiple analytical techniques (DSC, TGA, HPLC, XRPD, GC, etc) and proven ability to work in a lab setting. Working knowledge of modalities outside of traditional small molecule (Oligonucleotides, Protacs) and in silico predictive tools/modeling highly valued TRAVEL REQUIREMENTS: May require approximately 5-10% travel. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Cambridge, MA U.S. Base Salary Range: $116,000.00 - $182,270.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Cambridge, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Keywords: Takeda, Plymouth , Scientist - Analytical Development Early Stage, Science, Research & Development , Cambridge, Massachusetts