Director, Program Leadership & Management

Company: Deciphera Pharmaceuticals
Location: Waltham
Posted on: February 21, 2026

Job Description:

Job Description Job Description Job Description We are seeking a dynamic Director, Program Leadership & Management, to provide leadership, strategic direction and program management to our Development and Commercial Program Teams. In partnership with the Program Lead, the Director, Program Leadership & Management will drive development and deliver results for programs in early to late phase clinical development and/or lifecycle management programs. The successful candidate should possess and demonstrate a firm understanding of drug development, be comfortable with ambiguity, and have strong communication skills, enabling effective communication within program teams and throughout the organization. This role is highly cross-functional and will involve collaboration with internal and potentially external partners. In partnership with the Program Lead, the Director, Program Leadership & Management is charged with leading daily program management activities, including the development and execution of the program’s Integrated Development Strategy. He/she/they is expected to understand the overall program strategy and critical path activities, including risks and potential mitigation plans. Key Responsibilities: Strategic partner to the Program Lead, enabling development and ensuring execution of the Integrated Development Strategy- 50% In partnership with the Program Lead, drives the development and execution of strategic, integrated development plans through effective leadership of Program Teams Provides clear direction on product development requirements to meet the expectations of external customers and business stakeholders Monitors program progress and related KPIs, identifies gaps and risks and makes strategic recommendations Supports the execution and continuous re-assessment of development strategy in support of the overarching corporate strategy Ensures the effective and consistent operation of high-functioning program teams – 50% Facilitates program team mtgs to ensure productive and efficient discussion Ensures clear and timely communication of program strategy and progress to relevant stakeholders Orchestrates the integration of sub-teams to support the effectors of Program Teams Other duties and responsibilities as assigned Qualifications Required Qualifications Bachelor’s or Master’s with 12 years of R&D and/or drug development project management experience Strong organizational and communication skills Demonstrated knowledge of the drug development process Knowledge of project management software/tools Ability to manage team dynamics and handle multiple projects Preferred Capabilities Experience supporting a clinical trial Experience in developing drugs for oncology, neurology and/or orphan diseases Additional Information Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $189,000 - $259,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.? Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable) EQUAL EMPLOYMENT OPPORTUNITY INFORMATION Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.

Keywords: Deciphera Pharmaceuticals, Plymouth , Director, Program Leadership & Management, Executive , Waltham, Massachusetts